Enzymatic Production of Lauroyl and Stearoyl Monoesters of d-Xylose, l-Arabinose, and d-Glucose as Potential Lignocellulosic-Derived Products, and Their Evaluation as Antimicrobial Agents

Forestry and agricultural industries constitute highly relevant economic activities globally. They generate large amounts of residues rich in lignocellulose that have the potential to be valorized used different industrial processes. Producing renewable fuels high-value-added compounds from lignocellulosic biomass is a key aspect sustainable strategies central biorefinery concept. In this study, use biomass-derived monosaccharides for enzymatic synthesis sugar fatty acid esters (SFAEs) with antimicrobial activity was investigated valorize these agro-industrial residues. With aim evaluate if could substrates SFAEs, d-xylose, l-arabinose, d-glucose, lauroyl stearoyl monoesters were synthetized by transesterification reactions catalyzed Lipozyme RM IM as biocatalyst. The performed using commercial d-glucose separately substrates, 74:13:13 mixture sugars. proportion latter corresponds composition found hemicellulose sugarcane bagasse switchgrass, previously described literature. Products characterized nuclear magnetic resonance (NMR) spectroscopy showed only primary hydroxyl group involved esterification reaction. Antimicrobial assay several microorganisms 5-O-lauroyl-d-xylofuranose 5-O-lauroyl-l-arabinofuranose ability inhibit growth Gram-positive bacteria products mix. Furthermore, product exhibited against Candida albicans yeast, four tested filamentous fungi. These results suggest obtained resources produced green methods are promising agents.